TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples (2024)

  • Li, H. et al. Current trends in quantitative proteomics—an update. J. Mass Spectrom. 52, 319–341 (2017).

    Article CAS Google Scholar

  • Pappireddi, N., Martin, L. & Wuhr, M. A review on quantitative multiplexed proteomics. Chem. Bio. Chem. 20, 1210–1224 (2019).

    Article CAS Google Scholar

  • Thompson, A. et al. Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS. Anal. Chem. 75, 1895–1904 (2003).

    Article CAS Google Scholar

  • Rauniyar, N. & Yates, J. R. 3rd Isobaric labeling-based relative quantification in shotgun proteomics. J. Proteome Res. 13, 5293–5309 (2014).

    Article CAS Google Scholar

  • Vasaikar, S. et al. Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities. Cell 177, 1035–1049 e1019 (2019).

    Article CAS Google Scholar

  • Chick, J. M. et al. Defining the consequences of genetic variation on a proteome-wide scale. Nature 534, 500–505 (2016).

    Article CAS Google Scholar

  • Dayon, L. et al. Relative quantification of proteins in human cerebrospinal fluids by MS/MS using 6-plex isobaric tags. Anal. Chem. 80, 2921–2931 (2008).

    Article CAS Google Scholar

  • Paulo, J. A. et al. Effects of MEK inhibitors GSK1120212 and PD0325901 in vivo using 10-plex quantitative proteomics and phosphoproteomics. Proteomics 15, 462–473 (2015).

    Article CAS Google Scholar

  • Stepanova, E., Gygi, S. P. & Paulo, J. A. Filter-based protein digestion (FPD): a detergent-free and scaffold-based strategy for TMT workflows. J. Proteome Res. 17, 1227–1234 (2018).

    Article CAS Google Scholar

  • McAlister, G. C. et al. Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses. Anal. Chem. 84, 7469–7478 (2012).

    Article CAS Google Scholar

  • Thompson, A. et al. TMTpro: design, synthesis, and initial evaluation of a proline-based isobaric 16-plex tandem mass tag reagent set. Anal. Chem. 91, 15941–15950 (2019).

    Article CAS Google Scholar

  • McAlister, G. C. et al. MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes. Anal. Chem. 86, 7150–7158 (2014).

    Article CAS Google Scholar

  • Erickson, B. K. et al. Active instrument engagement combined with a real-time database search for improved performance of sample multiplexing workflows. J. Proteome Res. 18, 1299–1306 (2019).

    Article CAS Google Scholar

  • Schweppe, D. K. et al. Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics. Preprint at bioRxiv https://doi.org/10.1101/668533 (2019).

  • Kim, J. & Guan, K. L. mTOR as a central hub of nutrient signalling and cell growth. Nat. Cell Biol. 21, 63–71 (2019).

    Article CAS Google Scholar

  • Saxton, R. A. & Sabatini, D. M. mTOR Signaling in growth, metabolism, and disease. Cell 169, 361–371 (2017).

    Article CAS Google Scholar

  • Thoreen, C. C. et al. An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J. Biol. Chem. 284, 8023–8032 (2009).

    Article CAS Google Scholar

  • Navarrete-Perea, J., Yu, Q., Gygi, S. P. & Paulo, J. A. Streamlined tandem mass tag (SL-TMT) protocol: an efficient strategy for quantitative (phospho)proteome profiling using tandem mass tag-synchronous precursor selection-MS3. J. Proteome Res. 17, 2226–2236 (2018).

    Article CAS Google Scholar

  • Mizushima, N. A brief history of autophagy from cell biology to physiology and disease. Nat. Cell Biol. 20, 521–527 (2018).

    Article CAS Google Scholar

  • Dikic, I. & Elazar, Z. Mechanism and medical implications of mammalian autophagy. Nat. Rev. Mol. Cell Biol. 19, 349–364 (2018).

    Article CAS Google Scholar

  • An, H. et al. TEX264 Is an endoplasmic reticulum-resident ATG8-interacting protein critical for ER remodeling during nutrient stress. Mol. Cell. 74, 891–908 e810 (2019).

    Article CAS Google Scholar

  • Wu, R. et al. Correct interpretation of comprehensive phosphorylation dynamics requires normalization by protein expression changes. Mol. Cell Proteom. 10, M111 009654 (2011).

    Article Google Scholar

  • Ben-Sahra, I., Howell, J. J., Asara, J. M. & Manning, B. D. Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1. Science 339, 1323–1328 (2013).

    Article CAS Google Scholar

  • Barilari, M. et al. ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J. 36, 736–750 (2017).

    Article CAS Google Scholar

  • Gaetani, M. et al. Proteome integral solubility alteration: a high-throughput proteomics assay for target deconvolution. J. Proteome Res. 18, 4027–4037 (2019).

    Article CAS Google Scholar

  • Savitski, M. M. et al. Tracking cancer drugs in living cells by thermal profiling of the proteome. Science 346, 1255784 (2014).

    Article Google Scholar

  • Harding, S. D. et al. The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY. Nucleic Acids Res. 46, D1091–D1106 (2018).

    Article CAS Google Scholar

  • Becher, I. et al. Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat. Nat. Chem. Biol. 12, 908–910 (2016).

    Article CAS Google Scholar

  • Dai, L. et al. Horizontal cell biology: monitoring global changes of protein interaction states with the proteome-wide cellular thermal shift assay (CETSA). Annu. Rev. Biochem. 88, 383–408 (2019).

    Article CAS Google Scholar

  • Savitski, M. M. et al. Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis. Cell 173, 260–274 e225 (2018).

    Article CAS Google Scholar

  • Zecha, J. et al. Peptide level turnover measurements enable the study of proteoform dynamics. Mol. Cell Proteom. 17, 974–992 (2018).

    Article CAS Google Scholar

  • Dephoure, N. & Gygi, S. P. Hyperplexing: a method for higher-order multiplexed quantitative proteomics provides a map of the dynamic response to rapamycin in yeast. Sci. Signal. 5, rs2 (2012).

    Article Google Scholar

  • Hebert, A. S. et al. Neutron-encoded mass signatures for multiplexed proteome quantification. Nat. Methods 10, 332–334 (2013).

    Article CAS Google Scholar

  • Mulvey, C. M. et al. Using hyperLOPIT to perform high-resolution mapping of the spatial proteome. Nat. Protoc. 12, 1110–1135 (2017).

    Article CAS Google Scholar

  • Hughes, C. S. et al. Single-pot, solid-phase-enhanced sample preparation for proteomics experiments. Nat. Protoc. 14, 68–85 (2019).

    Article CAS Google Scholar

  • Elias, J. E. & Gygi, S. P. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat. Methods 4, 207–214 (2007).

    Article CAS Google Scholar

  • Huttlin, E. L. et al. A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174–1189 (2010).

    Article CAS Google Scholar

  • Savitski, M. M., Wilhelm, M., Hahne, H., Kuster, B. & Bantscheff, M. A scalable approach for protein false discovery rate estimation in large proteomic data sets. Mol. Cell Proteom. 14, 2394–2404 (2015).

    Article CAS Google Scholar

  • Beausoleil, S. A., Villen, J., Gerber, S. A., Rush, J. & Gygi, S. P. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Nat. Biotechnol. 24, 1285–1292 (2006).

    Article CAS Google Scholar

  • Huang da, W., Sherman, B. T. & Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44–57 (2009).

    Article Google Scholar

  • TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples (2024)

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